Formula for constipation

Enfamil Reguline has the best record for constipation: 38 of 38 parents said their baby's poops got softer or more regular, and more parents weighed in on it than on any other formula here. The three Kendamil formulas come next, starting with Kendamil Organic Formula at 21 of 27, and Similac 360 Total Care has the weakest record here at 3 of 13. Babies differ, and parents often switch formulas because of a problem, so read these as parent reports, not a promise for your baby.

  • 270 store reviews counted
  • Target shoppers
  • Oct 2018 to Oct 2026

Updated . How we count

Did poops get softer? What parents said
  1. Enfamil Reguline 38 said either way
  2. Kendamil Organic Formula 27 said either way
  3. Kendamil Goat Formula 20 said either way
  4. Kendamil Classic Formula 27 said either way
  5. Similac Pro-Total Comfort 28 said either way
  6. Similac 360 Total Care Sensitive 14 said either way
  7. Similac 360 Total Care 13 said either way

Share of parents who stated an outcome for constipation. Ranked by the lower bound of a 90% confidence interval, so a product needs both a good share and enough reports to rank high.

Enfamil Reguline Best record Enfamil Reguline 38 of 38 say poops got softer or more regular See price & reviews on Amazon
What stands out

Constipation complaints gather on the Similac formulas: 50% of Similac 360 Total Care reviews, 36% of Similac 360 Total Care Sensitive reviews and 32% of Similac Pro-Total Comfort reviews mention it. Among the Kendamil formulas, Kendamil Classic Formula draws the same complaint in 28% of reviews.

The ranking, product by product

Praise and complaints are the points parents repeat most, shown as a share of each product's counted store reviews.

1 Enfamil Reguline

Enfamil

Reguline

38/38 say poops got softer or more regular

Every parent who weighed in said poops got softer or more regular (38 of 38), and Enfamil's own site agrees at 10 of 10, which we show but don't count. Complaints are few, with 8% calling it too expensive and 5% mentioning more spit-up.

What parents praise

  • Less gas or fussing 10%
  • Good value 8%
  • Less spit-up 5%

What parents complain about

  • Too expensive 8%
  • More spit-up 5%
Where parents said it
  • Target 38 of 38
  • Brand site 10 of 10 shown, not counted
2

Kendamil

Organic Formula

21/27 say poops got softer or more regular

52% of reviews mention better poops and 20% say their baby likes the taste. Still, 18% mention constipation and 15% say it clumps or foams.

What parents praise

  • Less spit-up 28%
  • Baby likes the taste 20%
  • Less gas or fussing 15%
  • Mixes well 5%

What parents complain about

  • Clumps or foams 15%
  • Still gassy or fussy 15%
  • More spit-up 5%
Where parents said it
  • Target 21 of 27
  • Brand site 8 of 8 shown, not counted

Share of 40 store reviews that mention each point. A full bar is 50%.

3

Kendamil

Goat Formula

15/20 say poops got softer or more regular

Parents mention more than poops here, with 28% of reviews saying their baby was less gassy or fussy, though 18% say their baby stayed gassy. Kendamil's own site agrees at 9 of 9, which we show but don't count.

What parents praise

  • Less gas or fussing 28%
  • Baby likes the taste 23%
  • Less spit-up 13%
  • Mixes well 8%
  • Good value 5%

What parents complain about

  • Still gassy or fussy 18%
  • Too expensive 10%
  • More spit-up 10%
Where parents said it
  • Target 15 of 20
  • Brand site 9 of 9 shown, not counted

Share of 40 store reviews that mention each point. A full bar is 50%.

4

Kendamil

Classic Formula

17/27 say poops got softer or more regular

A split record at 17 of 27. 28% of reviews mention constipation, even though 38% mention less gas or fussing and 15% call it good value.

What parents praise

  • Less gas or fussing 38%
  • Baby likes the taste 25%
  • Less spit-up 20%
  • Good value 15%
  • Mixes well 8%

What parents complain about

  • More spit-up 13%
  • Still gassy or fussy 8%
  • Baby refused it 5%
Where parents said it
  • Target 17 of 27
  • Brand site 6 of 7 shown, not counted

Share of 40 store reviews that mention each point. A full bar is 50%.

5

Similac

Pro-Total Comfort

15/28 say poops got softer or more regular

Mixing is the main complaint, with 40% saying it clumps or foams, and 32% of reviews mention constipation. Similac's own site is less positive at 1 of 5, which we show but don't count.

What parents praise

  • Less gas or fussing 25%
  • Less spit-up 15%
  • Baby likes the taste 5%

What parents complain about

  • Clumps or foams 40%
  • Still gassy or fussy 30%
  • Too expensive 8%
Where parents said it
  • Target 15 of 28
  • Brand site 1 of 5 shown, not counted

Share of 40 store reviews that mention each point. A full bar is 50%.

6

Similac

360 Total Care Sensitive

7/14 say poops got softer or more regular

Parents are split down the middle at 7 of 14. 50% mention better poops, but 36% mention constipation and 18% call it too expensive.

What parents praise

  • Less gas or fussing 32%
  • Good value 9%
  • Baby likes the taste 9%
  • Less spit-up 9%
  • Mixes well 9%

What parents complain about

  • Too expensive 18%
  • Still gassy or fussy 18%
Where parents said it
  • Target 7 of 14

Share of 22 store reviews that mention each point. A full bar is 50%.

7

Similac

360 Total Care

3/13 say poops got softer or more regular

It has the weakest record here at 3 of 13, with 50% of reviews mentioning constipation and 36% saying their baby stayed gassy or fussy. 41% still mention better poops, a reminder that babies differ.

What parents praise

  • Less gas or fussing 23%
  • Baby likes the taste 18%

What parents complain about

  • Still gassy or fussy 36%
  • Too expensive 18%
  • Clumps or foams 9%
Where parents said it
  • Target 3 of 13
  • Brand site 0 of 4 shown, not counted

Share of 22 store reviews that mention each point. A full bar is 50%.

Where these numbers come from

The 7 products ranked here carry 12,410 reviews at Target. We read the newest reviews of each product (up to a thousand per listing), kept the ones that talk about constipation, and counted up to 40 per product, posted between Oct 2018 and Oct 2026.

A review counts only when the reviewer used the product themselves. We drop reviews written in exchange for a free product or a sweepstakes entry (0 on this page), and products that are no longer sold.

Target also shows reviews first posted on brands' own websites. We show them on product cards but never count them, because brand-site reviews run more positive than store reviews of the same products.

Because we searched for the problem, people who had it are overrepresented. Compare products with each other rather than reading a share as your own odds.

We count what parents report. Nothing here is medical or safety advice: for a sick baby, call your pediatrician, and for car seats, a certified child passenger safety technician can check the install.

Amazon buttons appear only on products that most parents here say fix the problem (at least 60%, with enough reviews to trust it). Everything else gets no buy link.

An AI model labels each review against a fixed list of points, and we spot-check the labels before publishing. We publish counts, never the reviews themselves.

Read the full method

Product pages we read

  1. Enfamil Reguline Target (40 reviews counted)
  2. Kendamil Organic Formula Target (40 reviews counted)
  3. Kendamil Goat Formula Target (40 reviews counted)
  4. Kendamil Classic Formula Target (40 reviews counted)
  5. Similac Pro-Total Comfort Target (40 reviews counted)
  6. Similac 360 Total Care Sensitive Target (22 reviews counted)
  7. Similac 360 Total Care Target (22 reviews counted)

Questions buyers ask

Which formula do parents say helped with constipation?

Enfamil Reguline has the best record (38 of 38), followed by Kendamil Organic Formula (21 of 27) and Kendamil Goat Formula (15 of 20). Reguline is a product name, not proof it will work for your baby. These are parent reports, and every baby is different.

What do parents say about the Similac formulas?

They draw more constipation complaints than the Enfamil and Kendamil formulas here. Similac Pro-Total Comfort sits at 15 of 28, Similac 360 Total Care Sensitive at 7 of 14 and Similac 360 Total Care at 3 of 13, and 50% of Similac 360 Total Care reviews mention constipation.

When should I call the pediatrician about constipation?

Talk to your pediatrician before switching formulas. Call right away if your baby's belly is hard and swollen, there is blood in the stool, or your baby is vomiting or isn't gaining weight. Parents often switch formulas because of a problem, and what worked for one baby may not work for yours.

How should I mix formula?

Exactly as the label says, with the scoop from the can and the amount of water listed. Don't add extra powder, extra water or anything else to the bottle unless your pediatrician tells you to.

Related problems

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